Question · asked by 0 reviews

Vitamin C vs placebo: Mortality (pneumonia-associated)

It is very uncertain whether vitamin C changes mortality due to pneumonia Defined as deaths due to pneumonia Dose:… compared with placebo (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Vitamin C vs placebo
Mortality due to pneumonia Defined as deaths due to pneumonia Dose: 200 mg · children under 5 years of age and adults
It is very uncertain whether vitamin C changes mortality due to pneumonia Defined as deaths due to pneumonia Dose:… compared with placebo (very low certainty).
Vitamin C supplementation for prevention and treatment of pneumonia (2020) · Cochrane Headline outcomes onlyearlier version CD013134.PUB2, superseded
RR 0.21 [0.03, 1.66]1 study · 57 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Vitamin C supplementation for prevention and treatment of pneumonia
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.