Question · asked by 1 review

Vitamin D compounds (supplementation) vs placebo or control: Subperiosteal erosions

Population
Adults with chronic kidney disease requiring dialysis
Intervention
Vitamin D compounds (supplementation)
Comparison
placebo or control
Outcome
Subperiosteal erosions

Meta-analysis of randomised trials of vitamin D supplementation for Subperiosteal erosions: RR 0.41 (95% CI 0.07 to 2.38), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Vitamin D compounds (supplementation) vs Placebo or control
Subperiosteal erosions · Adults with chronic kidney disease requiring dialysis
Meta-analysis of randomised trials of vitamin D supplementation for Subperiosteal erosions: RR 0.41 (95% CI 0.07 to 2.38), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) All outcomes
RR 0.41 [0.07, 2.38]3 studies · 120 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised…
2014 All outcomes
11 October 201355Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.