Question · asked by 1 review

Topical triamcinolone acetonide vs pimecrolimus 1%: Adverse effects

Population
People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Intervention
Topical triamcinolone acetonide
Comparison
pimecrolimus 1%
Outcome
Adverse effects

Topical triamcinolone acetonide showed no clear difference in adverse effects compared with topical pimecrolimus; GRADE not reported.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Topical triamcinolone acetonide vs Topical pimecrolimus
Adverse effects · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment · end of treatment
Topical triamcinolone acetonide showed no clear difference in adverse effects compared with topical pimecrolimus; GRADE not reported.
Interventions for treating oral lichen planus: corticosteroid therapies (2020) · Cochrane All outcomes
RR 0.21 [0.01, 4.10]1 study · 35 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating oral lichen planus: corticosteroid therapies
2020 · Cochrane All outcomes
2019-02Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.