Question · asked by 1 review

Vi‐rEPA vaccine (2 doses) vs control: Incidence of typhoid fever – year 1

Vi‐rEPA vaccine (2 doses) probably leads to lower incidence of typhoid fever – year 1 compared with control (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Vi‐rEPA vaccine (2 doses) vs control
Incidence of typhoid fever – year 1 · adults and children of 2 years of age and older
Vi‐rEPA vaccine (2 doses) probably leads to lower incidence of typhoid fever – year 1 compared with control (moderate certainty).
Vaccines for preventing typhoid fever (2018) · Cochrane Headline outcomes only
RR 0.06 [0.01, 0.25]1 study · 12008 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Vaccines for preventing typhoid fever
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.