Question · asked by 1 review

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations): Adverse effects

Population
Children and adults (with or without carious lesions)
Intervention
Silver diamine fluoride (SDF) plus fluoride varnish
Comparison
Sealants plus fluoride varnish (with or without restorations)
Outcome
Adverse effects

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)
Adverse effects · Children and adults (with or without carious lesions) · Study period (24 months), Children
Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults (2024) · Cochrane All outcomes
Ruff 2022 reported that there were no adverse events during the study period; adverse events were not defined by the study authors. Assumed data available for 1398 participants.1 study · 1398 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults
2024 · Cochrane All outcomes
2023-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.