Question · asked by 1 review
Sulodexide (heparin plus dermatan sulphate chains) vs placebo: Days to resolution of pain / epithelialization; number of aphthae per month
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Sulodexide (heparin plus dermatan sulphate chains) vs Placebo Days to resolution of pain / epithelialization; number of aphthae per month · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and… Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) (2012) · Cochrane All outcomes | The trial by Femiano 2003 (high risk of bias) also compared sulodexide with placebo. Data were incompletely presented (ranges/totals only) precluding further analysis. | 1 study · 20 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes | 2012-06 | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.