Cephalosporins vs penicillin: Adverse events (ITT analysis)
It is very uncertain whether cephalosporins changes adverse events (ITT analysis) compared with penicillin (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Cephalosporins vs penicillin Adverse events (ITT analysis) · group A streptococcal pharyngitis It is very uncertain whether cephalosporins changes adverse events (ITT analysis) compared with penicillin (very low certainty). Different antibiotic treatments for group A streptococcal pharyngitis (2023) · Cochrane Headline outcomes only | OR 0.94 [0.27, 3.25] | 3 studies · 1279 participants | Very low |
Cephalosporins vs penicillin Adverse events (ITT analysis) · group A streptococcal pharyngitis It is very uncertain whether cephalosporins changes adverse events (ITT analysis) compared with penicillin (very low certainty). Different antibiotic treatments for group A streptococcal pharyngitis (2021) · Cochrane Headline outcomes onlyearlier version CD004406.PUB5, superseded | OR 0.94 [0.27, 3.25] | 3 studies · 1279 participants | Very low |
Cephalosporins vs penicillin Adverse events (ITT analysis) · group A streptococcal pharyngitis It is very uncertain whether cephalosporins changes adverse events (ITT analysis) compared with penicillin (very low certainty). Different antibiotic treatments for group A streptococcal pharyngitis (2016) · Cochrane Headline outcomes onlyearlier version CD004406.PUB4, superseded | OR 0.94 [0.27, 3.25] | 3 studies · 1279 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.