Question · asked by 1 review
Oral clonazepam (benzodiazepine) vs placebo: Withdrawals due to adverse events
- Population
- Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of minimum 3 months' duration
- Intervention
- Oral clonazepam (benzodiazepine)
- Comparison
- placebo
- Outcome
- Withdrawals due to adverse events
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral clonazepam (benzodiazepine) vs Placebo Adverse events (withdrawals due to adverse effects) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to… · 60 days Pharmacological interventions for pain in patients with temporomandibular disorders (2010) · Cochrane All outcomes | One participant in the clonazepam group withdrew from the study by Harkins et al 1991 due to severe headache. | 1 study · 20 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes | 2010-08 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.