IV vs oral cyclophosphamide: Adverse effects ‐ Bacterial infection clinical assessment
It is very uncertain whether IV changes adverse events: bacterial infection compared with oral cyclophosphamide (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
IV vs oral cyclophosphamide Adverse events: bacterial infection · idiopathic steroid‐resistant nephrotic syndrome in children It is very uncertain whether IV changes adverse events: bacterial infection compared with oral cyclophosphamide (very low certainty). Interventions for idiopathic steroid‐resistant nephrotic syndrome in children (2019) · Cochrane Headline outcomes only | RR 1.02 [0.1, 10.62] | 2 studies · 61 participants | Very low |
IV vs oral cyclophosphamide Adverse effects ‐ Bacterial infection clinical assessment · patients with idiopathic steroid‐resistant nephrotic syndrome in children Interventions for idiopathic steroid‐resistant nephrotic syndrome in children (2010) · Cochrane Headline outcomes onlyearlier version CD003594.PUB4, superseded | no estimate extracted | 1 study · 11 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for idiopathic steroid‐resistant nephrotic syndrome in children 2019 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.