GERD vs Healthy individuals without reflux (controls): Dental caries
- Population
- Adults with gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR)
- Intervention
- GERD
- Comparison
- Healthy individuals without reflux (controls)
- Outcome
- Dental caries
Reflux appears associated with a higher prevalence of dental caries than in healthy individuals based on three studies, though to a lesser extent than erosion; evidence is ungraded and not pooled.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
GERD vs Healthy individuals without reflux (controls) Dental caries (Decayed Missing Filled index) · Adults with gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR) · Adult patients in gastroenterology, ENT and dental clinical settings Reflux appears associated with a higher prevalence of dental caries than in healthy individuals based on three studies, though to a lesser extent than erosion; evidence is ungraded and not pooled. Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020) All outcomes | Three studies reported higher decayed-missing-filled index scores or a positive association between GERD and caries compared with controls (Yoshikawa, Song, Watanabe); no pooled estimate. | 3 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. 2020 All outcomes | January 1990 to December 2019 (publication period searched) | 24 | Not applicable |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- GERD vs Healthy controls · adults · 1 review
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Oral soft tissue disorders are associated with gastroesophageal reflux disease: retrospective study. · 2017 · included by 1 of these review
- The relationship between gastroesophageal reflux disease and chronic periodontitis. · 2014 · included by 1 of these review
- Oral symptoms including dental erosion in gastroesophageal reflux disease are associated with decreased salivary flow volume and… · 2011 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.