Question · asked by 1 review

Neutron radiotherapy vs Conventional photon radiotherapy: Total mortality

Population
People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials eligible where more than 50% of participants had oral cavity or oropharyngeal cancer (or separate data available)
Intervention
Neutron radiotherapy
Comparison
Conventional photon radiotherapy
Outcome
Total mortality

Neutron radiotherapy showed no clear difference in total mortality compared with conventional photon radiotherapy; GRADE not reported.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Neutron radiotherapy vs Conventional photon radiotherapy
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and…
Neutron radiotherapy showed no clear difference in total mortality compared with conventional photon radiotherapy; GRADE not reported.
Interventions for the treatment of oral cavity and oropharyngeal cancer: radiotherapy (2010) · Cochrane All outcomes
HR 1.10 [0.90, 1.34]3 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for the treatment of oral cavity and oropharyngeal cancer: radiotherapy
2010 · Cochrane All outcomes
2010-07Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.