Question · asked by 1 review

Nebulised hypertonic saline vs nebulised 0.9% saline: Clinical severity score (post‐treatment) at day 2

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Nebulised hypertonic saline vs nebulised 0.9% saline
Clinical severity score (post‐treatment) at day 2 · infants up to 24 months of age with acute bronchiolitis
Nebulised hypertonic saline solution for acute bronchiolitis in infants (2023) · Cochrane Headline outcomes only
no estimate extracted10 studies · 907 participantsLow
Nebulised hypertonic saline vs nebulised 0.9% saline
Clinical severity score (post‐treatment) at day 2 · infants up to 24 months of age with acute bronchiolitis
Nebulised hypertonic saline solution for acute bronchiolitis in infants (2017) · Cochrane Headline outcomes onlyearlier version CD006458.PUB4, superseded
no estimate extracted8 studies · 603 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Nebulised hypertonic saline solution for acute bronchiolitis in infants
2023 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.