Question · asked by 1 review
Hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy vs conventional therapy: Healing of MRONJ
- Population
- People with established (manifest) MRONJ
- Intervention
- Hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy
- Comparison
- conventional therapy
- Outcome
- Healing of MRONJ
It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy vs Conventional therapy Healing of MRONJ · People with established (manifest) MRONJ · up to 24 months (at last follow-up) It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty). Interventions for managing medication‐related osteonecrosis of the jaw (2022) · Cochrane All outcomes | RR 1.56 [0.77, 3.18] | 1 study · 46 participants | Very low |
Hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy vs Conventional therapy Healing of MRONJ · People with established (manifest) MRONJ · up to 24 months (at last follow-up) It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty). Interventions for managing medication‐related osteonecrosis of the jaw (2017) · Cochrane All outcomesearlier version CD012432.PUB2, superseded | RR 1.56 [0.77, 3.18] | 1 study · 46 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes | 2021-06 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.