Fluoride varnish vs Non-fluoride (placebo) varnish: Number of participants with more severe DLs (score 3 or 4 versus 1 or 2)
Professionally-applied fluoride varnish (7700 ppm F ammonium… may leads to lower number of participants with more severe DLs (score 3 or 4 versus 1… compared with non-fluoride (placebo) varnish (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Professionally-applied fluoride varnish (7700 ppm F ammonium fluoride), every 6 weeks vs Non-fluoride (placebo) varnish Number of participants with more severe DLs (score 3 or 4 versus 1 or 2) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond; follow-up 1.7 years Professionally-applied fluoride varnish (7700 ppm F ammonium… may leads to lower number of participants with more severe DLs (score 3 or 4 versus 1… compared with non-fluoride (placebo) varnish (low certainty). Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane All outcomes | RR 0.46 [0.22, 0.95] | 1 study · 148 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes | 1 February 2019 | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.