Question · asked by 1 review

Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted): Negative LR for detecting advanced occlusal caries

Population
Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
Intervention
Radiographic caries detection (bitewing radiography)
Comparison
Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted)
Outcome
Negative LR for detecting advanced occlusal caries

In the conventional (all-studies) meta-analysis, the negative lr of radiographic detection for advanced occlusal caries was 0.53 (95% CI 0.46 to 0.62) (ungraded).

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted)
Negative LR for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Conventional meta-analysis (all studies)
In the conventional (all-studies) meta-analysis, the negative lr of radiographic detection for advanced occlusal caries was 0.53 (95% CI 0.46 to 0.62) (ungraded).
Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) All outcomes
Negative LR 0.53 [0.46, 0.62]44 studiesGRADE not reported
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted)
Negative LR for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Public health clinic, Giza (Cairo), Egypt, Tailored to Egypt
In the meta-analysis tailored to Egypt, the negative lr of radiographic detection for advanced occlusal caries was 0.51 (95% CI 0.44 to 0.6) (ungraded).
Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) All outcomes
Negative LR 0.51 [0.44, 0.6]38 studiesGRADE not reported
Radiographic caries detection (bitewing radiography) vs Reference standard (histological validation or cavity/lesion opening; advanced = cavitated/dentin-involved lesions, all = enamel-confined initial lesions also counted)
Negative LR for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly… · Private practice, rural northern Germany, Tailored to Germany
In the meta-analysis tailored to Germany, the negative lr of radiographic detection for advanced occlusal caries was 0.54 (95% CI 0.46 to 0.63) (ungraded).
Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and… (2018) All outcomes
Negative LR 0.54 [0.46, 0.63]36 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Visual and radiographic caries detection: a tailored meta-analysis for two different settings, Egypt and Germany.
2018 All outcomes
Not specified (data reused from two source systematic reviews, Gimenez 2015 and Schwendicke 2015)2Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.