Question · asked by 1 review

Higher number of lost teeth (per one additional lost tooth) vs One fewer missing tooth: Malignant transformation (oral cancer development)

Population
Adults in case-control studies (oral cancer patients vs healthy controls)
Intervention
Higher number of lost teeth (per one additional lost tooth)
Comparison
One fewer missing tooth
Outcome
Malignant transformation (oral cancer development)

The number of missing teeth (per tooth) was not significantly associated with oral cancer (OR 0.96, 95% CI 0.92-1.01); ungraded.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Number of missing teeth (per additional tooth) vs One fewer missing tooth
Oral cancer (OC) · Adults in case-control studies of oral cancer · Not specified, Case-control studies conducted in Asia (n=6), Europe (n=5), USA (n=2) and other countries (n=3), Missing teeth (per tooth)
The number of missing teeth (per tooth) was not significantly associated with oral cancer (OR 0.96, 95% CI 0.92-1.01); ungraded.
Periodontitis and the risk of oral cancer: a meta-analysis of case-control studies. (2024) All outcomes
OR 0.96 [0.92, 1.01]2 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Periodontitis and the risk of oral cancer: a meta-analysis of case-control studies.
2024 All outcomes
Up to September 2023 (databases from inception)16Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.