Question · asked by 1 review
Acarbose vs placebo: Serious adverse events
- Population
- people at increased risk for developing type 2 diabetes
- Intervention
- Acarbose
- Comparison
- placebo
- Outcome
- Serious adverse events
Acarbose showed no clear difference in serious adverse events compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Acarbose vs placebo Serious adverse events · people at risk of developing type 2 diabetes mellitus Acarbose showed no clear difference in serious adverse events compared with placebo (low certainty). Alpha‐glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated… (2018) · Cochrane Headline outcomes only | RR 1.12 [0.97, 1.29] | 2 studies · 6625 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Alpha‐glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased… 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Acarbose vs no intervention · people at increased risk for developing type 2 diabetes · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.