Question · asked by 1 review

Fluoride toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste: Acquiring extrinsic tooth staining (adverse effect; stannous fluoride toothpaste)

Population
Children and adolescents aged 16 years or less
Intervention
Fluoride toothpaste
Comparison
Non-fluoride (0 ppm F) placebo toothpaste
Outcome
Acquiring extrinsic tooth staining (adverse effect; stannous fluoride toothpaste)

Fluoride toothpaste led to higher acquiring extrinsic tooth staining (adverse effect; stannous… compared with placebo (non-fluoride) toothpaste; GRADE not reported.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Fluoride toothpaste vs Placebo (non-fluoride) toothpaste
Acquiring extrinsic tooth staining (adverse effect; stannous fluoride toothpaste) · Children and adolescents aged 16 years or less · At least 1 year
Fluoride toothpaste led to higher acquiring extrinsic tooth staining (adverse effect; stannous… compared with placebo (non-fluoride) toothpaste; GRADE not reported.
Fluoride toothpastes for preventing dental caries in children and adolescents (2003) · Cochrane All outcomes
RD 0.24 [0.19, 0.30]5 studies · 3948 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluoride toothpastes for preventing dental caries in children and adolescents
2003 · Cochrane All outcomes
2001-10Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.