Question · asked by 1 review

Antibody (T cell) vs steroids: Failure of acute rejection reversal

Antibody (T cell) probably leads to lower failure of reversal of acute rejection compared with steroid (stratified by antibody type) (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Antibody (T cell) vs steroid (stratified by antibody type)
Failure of reversal of acute rejection · kidney transplant recipients: first rejection episode
Antibody (T cell) probably leads to lower failure of reversal of acute rejection compared with steroid (stratified by antibody type) (moderate certainty).
Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients (2017) · Cochrane Headline outcomes only
RR 0.5 [0.3, 0.82]6 studies · 405 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.