Question · asked by 1 review

Platelet-rich fibrin (PRF) graft vs No grafting: Radiographic healing - 1 year

Population
People requiring retreatment of periapical lesions (failed root canal therapy)
Intervention
Platelet-rich fibrin (PRF) graft
Comparison
No grafting
Outcome
Radiographic healing - 1 year

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Platelet-rich fibrin (PRF) graft vs No grafting
Radiographic healing - 1 year · People requiring retreatment of periapical lesions (failed root canal therapy) · 1 year
Endodontic procedures for retreatment of periapical lesions (2016) · Cochrane All outcomes
Angerame 2015 (7 test, 4 control): no significant difference in healing of the lesion at 1 year; significant difference only at 2- and 3-month follow-up. Small preliminary study; no robust pooled analysis.1 study · 11 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Endodontic procedures for retreatment of periapical lesions
2016 · Cochrane All outcomes
2016-02-10Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.