Question · asked by 1 review

Morphine via patient-controlled analgesia (PCA) vs Morphine via continuous infusion (CI): Average pain scores (0-100 VAS)

Population: People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Intervention: Morphine via patient-controlled analgesia (PCA)
Comparison: Morphine via continuous infusion (CI)
Outcome: Average pain scores (0-100 VAS)

Morphine via patient-controlled analgesia (PCA) showed no clear difference in average pain scores (0-100 VAS) compared with morphine via continuous infusion (CI); GRADE not reported.

What each review found

Current versions only

No studies found 0 · 0%GRADE not reported 4 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Finding	Effect	Studies	GRADE certainty
Morphine via patient-controlled analgesia (PCA) vs Morphine via continuous infusion (CI) Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis Morphine via patient-controlled analgesia (PCA) showed no clear difference in average pain scores (0-100 VAS) compared with morphine via continuous infusion (CI); GRADE not reported. Interventions for treating oral mucositis for patients with cancer receiving treatment (2010) · Cochrane All outcomes	MD -2.49 [-12.28, 7.29]	3 studies · 113 participants	GRADE not reported
Morphine via patient-controlled analgesia (PCA) vs Morphine via continuous infusion (CI) Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis Morphine via patient-controlled analgesia (PCA) showed no clear difference in average pain scores (0-100 VAS) compared with morphine via continuous infusion (CI); GRADE not reported. Interventions for treating oral mucositis for patients with cancer receiving treatment (2007) · Cochrane All outcomesearlier version CD001973.PUB3, superseded	MD 1.03 [-8.86, 10.92]	3 studies · 111 participants	GRADE not reported
Morphine via patient-controlled analgesia (PCA) vs Morphine via continuous infusion (CI) Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis Morphine via patient-controlled analgesia (PCA) showed no clear difference in average pain scores (0-100 VAS) compared with morphine via continuous infusion (CI); GRADE not reported. Interventions for treating oral mucositis for patients with cancer receiving treatment (2004) · Cochrane All outcomesearlier version CD001973.PUB2, superseded	MD 1.03 [-8.86, 10.92]	3 studies · 111 participants	GRADE not reported
Morphine via patient-controlled analgesia (PCA) vs Morphine via continuous infusion (CI) Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis Morphine via patient-controlled analgesia (PCA) showed no clear difference in average pain scores (0-100 VAS) compared with morphine via continuous infusion (CI); GRADE not reported. Interventions for treating oral mucositis for patients with cancer receiving treatment (2001) · Cochrane All outcomesearlier version CD001973, superseded	MD 1.03 [-8.86, 10.92]	3 studies · 111 participants	GRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

Review	Searched up to	Included studies	AMSTAR 2
Interventions for treating oral mucositis for patients with cancer receiving treatment 2010 · Cochrane All outcomes	2010-06	Not listed	Not assessed

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.