Resin-based fissure sealant vs Fluoride varnish: Caries incidence of first permanent molars (FPMs)
- Population
- Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars
- Intervention
- Resin-based fissure sealant
- Comparison
- Fluoride varnish
- Outcome
- Caries incidence of first permanent molars (FPMs)
Pit and fissure sealant and fluoride varnish showed no statistically significant difference in caries incidence of first permanent molars at 24 months (RR 0.65, 95% CI 0.31 to 1.38; I2=89%; not GRADE-rated).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Resin-based pit and fissure sealant (PFS) vs Fluoride varnish (FV) Caries incidence in first permanent molars · Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars · 24 months, School-based caries prevention; schoolchildren (included trials aged 6-9 years) Pit and fissure sealant and fluoride varnish showed no statistically significant difference in caries incidence of first permanent molars at 24 months (RR 0.65, 95% CI 0.31 to 1.38; I2=89%; not GRADE-rated). Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A… (2022) All outcomes | RR 0.65 [0.31, 1.38] | 3 studies · 1263 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A Systematic Review and… 2022 All outcomes | Databases searched for studies from January 1980 to May 2022 (Methods 2.6), implying a May 2022 search; the Abstract instead states 1990-2019 | 7 | Critically Low / Critically Low |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.