Corticosteroids vs placebo or no treatment: Maternal death
- Population
- pregnant women at high risk of preterm birth receiving a corticosteroid or placebo/no treatment; women with singleton and multiple pregnancy and intact and ruptured membranes
- Intervention
- Corticosteroids
- Comparison
- placebo or no treatment
- Outcome
- Maternal death
Corticosteroids showed no clear difference in maternal death compared with placebo or no treatment (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Corticosteroids vs placebo or no treatment Maternal death · pregnant women at high risk of preterm birth receiving a corticosteroid or placebo/no treatment; women with singleton… Corticosteroids showed no clear difference in maternal death compared with placebo or no treatment (moderate certainty). Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (2017) · Cochrane Headline outcomes onlyearlier version CD004454.PUB3, superseded | RR 0.98 [0.06, 15.5] | 5 studies · 3392 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Corticosteroids vs placebo or no treatment · women at risk of preterm birth · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.