Question · asked by 1 review

Aclidinium bromide vs placebo: Quality of life: number of participants with clinically significant improvement (≥ 4 units) in SGRQ total score

Aclidinium bromide leads to higher quality of life Number of patients who achieved at least 4 units… compared with placebo (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Aclidinium bromide vs placebo
Quality of life Number of patients who achieved at least 4 units improvement in SGRQ total score · patients with stable chronic obstructive pulmonary disease
Aclidinium bromide leads to higher quality of life Number of patients who achieved at least 4 units… compared with placebo (high certainty).
Aclidinium bromide for stable chronic obstructive pulmonary disease (2014) · Cochrane Headline outcomes only
OR 1.49 [1.31, 1.7]7 studies · 4420 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Aclidinium bromide for stable chronic obstructive pulmonary disease
2014 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.