Remifentanil (PCA) vs epidural/CSE: Additional analgesia required (escape analgesia)
- Population
- women in labour with planned vaginal delivery
- Intervention
- Remifentanil (PCA)
- Comparison
- epidural/CSE
- Outcome
- Additional analgesia required (escape analgesia)
Remifentanil (PCA) probably leads to higher additional analgesia required compared with epidural/CSE (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Remifentanil (PCA) vs epidural/CSE Additional analgesia required · women in labour with planned vaginal delivery Remifentanil (PCA) probably leads to higher additional analgesia required compared with epidural/CSE (moderate certainty). Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in… (2017) · Cochrane Headline outcomes only | RR 9.27 [3.73, 23.03] | 6 studies · 1037 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Remifentanil (PCA) vs remifentanil (continuous IV) · women in labour with planned vaginal delivery · 1 review
- Remifentanil (PCA) vs another opioid (IV/IM) · women in labour with planned vaginal delivery · 1 review
- Remifentanil (PCA) vs another opioid (PCA) · women in labour with planned vaginal delivery · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.