Question · asked by 1 review
Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides: Blood ammonia concentrations (units unspecified)
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides Blood ammonia concentrations (units unspecified) · adults with cirrhosis and hepatic encephalopathy Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic… (2019) · Cochrane Headline outcomes only | no estimate extracted | 1 study · 35 participants | Very low |
Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides Blood ammonia concentrations (µg/dL) · adults with cirrhosis and hepatic encephalopathy Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic… (2019) · Cochrane Headline outcomes only | no estimate extracted | 1 study · 16 participants | Very low |
Phamacotherapies that specifically target ammonia vs placebo or non‐absorbable disaccharides Blood ammonia concentrations (µmol/L) · adults with cirrhosis and hepatic encephalopathy Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic… (2019) · Cochrane Headline outcomes only | no estimate extracted | 1 study · 231 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in adults with cirrhosis 2019 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.