Question · asked by 1 review
Oral diazepam vs placebo or no intervention: Behaviour
- Population
- Children and adolescents (0 to 16 years) needing dental treatment
- Intervention
- Oral diazepam
- Comparison
- placebo or no intervention
- Outcome
- Behaviour
It is very uncertain whether oral diazepam changes behaviour (Houpt/behavioural score) compared with placebo (including no intervention) (very low certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 2 · 66.7%Very low 1 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral diazepam vs Placebo (including no intervention) Behaviour (Houpt/behavioural score) · Children and adolescents (0 to 16 years) needing dental treatment It is very uncertain whether oral diazepam changes behaviour (Houpt/behavioural score) compared with placebo (including no intervention) (very low certainty). Sedation of children undergoing dental treatment (2018) · Cochrane All outcomes | SMD 0.62 [-0.28, 1.53] | 1 study · 20 participants | Very low |
Oral diazepam vs Placebo (including no intervention) Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2006) · Cochrane All outcomesearlier version CD003877.PUB3, superseded | Five diazepam placebo studies (oral x4; rectal x1): Gallardo 1984 and Yanase 1996 significant; Flaitz 1985a (rectal) significant; Lindsay 1985a/1985b no difference. Narrative; not pooled. | 5 studies | GRADE not reported |
Oral diazepam vs Placebo (including no intervention) Behaviour · Children and adolescents (0 to 16 years) needing dental treatment Sedation of children undergoing dental treatment (2005) · Cochrane All outcomesearlier version CD003877.PUB2, superseded | Five diazepam placebo studies (oral x4; rectal x1): Gallardo 1984 (0.5 mg/kg) and Yanase 1996 (0.3 mg/kg) significant behaviour improvement; Flaitz 1985a (rectal 0.6 mg/kg) significantly reduced interfering movements;… | 5 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Sedation of children undergoing dental treatment 2018 · Cochrane All outcomes | 22 February 2018 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.