Question · asked by 1 review

Pregabalin 300 mg or 600 mg vs placebo: Risk for at least one adverse event per patient

Population
adults with moderate or severe neuropathic pain
Intervention
Pregabalin 300 mg or 600 mg
Comparison
placebo
Outcome
Risk for at least one adverse event per patient

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Pregabalin 300 mg or 600 mg vs placebo
At least 1 AE · adults with moderate or severe neuropathic pain
Pregabalin for neuropathic pain in adults (2019) · Cochrane Headline outcomes only
no estimate extracted15 studies · 3697 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pregabalin for neuropathic pain in adults
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.