Anti‐VEGF vs laser: Gain 3+ lines of visual acuity at 1 year
Anti‐VEGF leads to higher gain 3+ lines of visual acuity at 1 year compared with laser (high certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Anti‐VEGF vs laser Gain 3+ lines of visual acuity at 1 year · people with diabetic macular oedema Anti‐VEGF leads to higher gain 3+ lines of visual acuity at 1 year compared with laser (high certainty). Anti‐vascular endothelial growth factor for diabetic macular oedema: a network meta‐analysis (2014) · Cochrane Headline outcomes onlyearlier version CD007419.PUB4, superseded | RR 3.6 [2.7, 4.8] | 10 studies · 1333 participants | High |
Anti‐VEGF vs laser Gain 3+ lines of visual acuity at 1 year · patients with diabetic macular oedema Anti‐VEGF probably leads to higher gain 3+ lines of visual acuity at 1 year compared with laser (moderate certainty). Anti‐vascular endothelial growth factor for diabetic macular oedema: a network meta‐analysis (2012) · Cochrane Headline outcomes onlyearlier version CD007419.PUB3, superseded | RR 3.2 [2.07, 4.95] | 5 studies · 556 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Anti‐vascular endothelial growth factor for diabetic macular oedema: a network meta‐analysis 2023 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.