Question · asked by 1 review

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone: Adverse effects (including quality of life)

Population
Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
Intervention
Combined HBO and perioperative antibiotics prior to dental implant therapy
Comparison
antibiotics alone
Outcome
Adverse effects (including quality of life)

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Combined HBO and perioperative antibiotics prior to dental implant therapy vs Antibiotics alone prior to dental implant therapy
Adverse effects (including quality of life) · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the… · 1 year
Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy (2019) · Cochrane All outcomes
This comparison was only made in 1 study which reported no serious adverse events associated with HBO therapy. Quality of life measures (oral status, functioning, satisfaction) showed emotional functioning and pain…1 study · 26 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy
2019 · Cochrane All outcomes
2019-11Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.