Question · asked by 1 review

Loratadine 10 mg vs placebo: Good or excellent response Global assessment of symptom scores

Loratadine 10 mg showed no clear difference in good or excellent response Global assessment of symptom scores compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Loratadine 10 mg vs placebo
Good or excellent response Global assessment of symptom scores · patients with chronic spontaneous urticaria
Loratadine 10 mg showed no clear difference in good or excellent response Global assessment of symptom scores compared with placebo (low certainty).
H1‐antihistamines for chronic spontaneous urticaria (2014) · Cochrane Headline outcomes only
RR 1.86 [0.91, 3.79]2 studies · 124 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
H1‐antihistamines for chronic spontaneous urticaria
2014 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.