Question · asked by 1 review

Pregabalin vs placebo: Lack of efficacy withdrawal

Population
adults with fibromyalgia
Intervention
Pregabalin
Comparison
placebo
Outcome
Lack of efficacy withdrawal

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Pregabalin vs placebo
Withdrawals due to lack of efficacy · adults with fibromyalgia enrolled in studies of classic design
Pregabalin for pain in fibromyalgia in adults (2016) · Cochrane Headline outcomes only
no estimate extracted5 studies · 1874 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pregabalin for pain in fibromyalgia in adults
2016 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.