Chlorhexidine vs Cryotherapy (ice chips) 60 minutes: Oral mucositis (any severity)
- Population
- Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
- Intervention
- Chlorhexidine
- Comparison
- Cryotherapy (ice chips) 60 minutes
- Outcome
- Oral mucositis (any severity)
Chlorhexidine showed no clear difference in oral mucositis (any severity) compared with cryotherapy (ice chips); GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorhexidine vs Cryotherapy (ice chips) Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · Median 28 days Chlorhexidine showed no clear difference in oral mucositis (any severity) compared with cryotherapy (ice chips); GRADE not reported. Interventions for preventing oral mucositis for patients with cancer receiving treatment (2011) · Cochrane All outcomes | RR 1.03 [0.76, 1.41] | 1 study · 133 participants | GRADE not reported |
Chlorhexidine vs Cryotherapy (ice chips) Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · Median 28 days Chlorhexidine showed no clear difference in oral mucositis (any severity) compared with cryotherapy (ice chips); GRADE not reported. Interventions for preventing oral mucositis for patients with cancer receiving treatment (2010) · Cochrane All outcomesearlier version CD000978.PUB4, superseded | RR 1.03 [0.76, 1.41] | 1 study · 133 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes | 2011-02 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Chlorhexidine vs placebo/no treatment · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · 1 review
- Chlorhexidine vs placebo/no treatment · Patients with cancer receiving chemotherapy and/or radiotherapy · 0 reviews
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.