Question · asked by 1 review
CR oxycodone vs IR oxycodone: Pain intensity (mean across treatment or at end of treatment; length of treatment varied across trials; various pain intensity scales; SMD)
- Population
- adults with cancer‐related pain
- Intervention
- CR oxycodone
- Comparison
- IR oxycodone
- Outcome
- Pain intensity (mean across treatment or at end of treatment; length of treatment varied across trials; various pain intensity scales; SMD)
It is very uncertain whether CR oxycodone changes pain intensity (mean across treatment or at end of treatment; length… compared with IR oxycodone (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
CR oxycodone vs IR oxycodone Pain intensity (mean across treatment or at end of treatment; length of treatment varied across trials; various pain intensity scales; SMD) · adults with cancer‐related pain It is very uncertain whether CR oxycodone changes pain intensity (mean across treatment or at end of treatment; length… compared with IR oxycodone (very low certainty). Oxycodone for cancer‐related pain (2022) · Cochrane Headline outcomes only | SMD 0.12 | 3 studies · 319 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oxycodone for cancer‐related pain 2022 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.