Question · asked by 0 reviews

Combined index tests (e.g. vital staining plus light-based detection or cytology) vs Scalpel, punch or fine needle aspiration biopsy with histological diagnosis: Sensitivity

Population
Adults (aged 16 years or over) presenting with clinically evident oral lesions
Intervention
Combined index tests (e.g. vital staining plus light-based detection or cytology)
Comparison
Scalpel, punch or fine needle aspiration biopsy with histological diagnosis
Outcome
Sensitivity

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Combined index tests (e.g. vital staining plus light-based detection or cytology) vs Scalpel, punch or fine needle aspiration biopsy with histological diagnosis
Sensitivity · Adults (aged 16 years or over) presenting with clinically evident oral lesions
Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically… (2015) · Cochrane All outcomesearlier version CD010276.PUB2, superseded
Vital Stain plus adjunct: Sensitivity Not possible (insufficient studies to perform meta-analysis); 402 participants / 478 lesions / 6 studies; median prevalence 0.27 (0.04 to 0.48); High risk of bias. Four studies…6 studies · 402 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions
2021 · Cochrane All outcomes
2020-10-20Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.