Question · asked by 1 review

Clobetasol propionate ointment vs 5% topical mesalazine gel in adhesive base: Pain reduction (VAS 0-10)

Population
People with erosive oral lichen planus
Intervention
Clobetasol propionate ointment
Comparison
5% topical mesalazine gel in adhesive base
Outcome
Pain reduction (VAS 0-10)

Clobetasol propionate ointment 0.05% showed no clear difference in pain reduction (VAS 0-10) compared with 5% topical mesalazine gel in adhesive base; GRADE not reported.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Clobetasol propionate ointment 0.05% vs 5% topical mesalazine gel in adhesive base
Pain reduction (VAS 0-10) · People with erosive oral lichen planus
Clobetasol propionate ointment 0.05% showed no clear difference in pain reduction (VAS 0-10) compared with 5% topical mesalazine gel in adhesive base; GRADE not reported.
Interventions for erosive lichen planus affecting mucosal sites (2012) · Cochrane All outcomes
MD -0.83 [-4.12, 2.46]1 study · 12 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for erosive lichen planus affecting mucosal sites
2012 · Cochrane All outcomes
2009-09Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.