Skin grafts and tissue replacements vs placebo or usual care: Total incidence of lower limb amputations
It is very uncertain whether skin grafts and tissue replacements changes total incidence of lower limb amputations compared with placebo or standard care (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Skin grafts and tissue replacements vs placebo or standard care Total incidence of lower limb amputations · People with diabetes who have foot ulcers It is very uncertain whether skin grafts and tissue replacements changes total incidence of lower limb amputations compared with placebo or standard care (very low certainty). Skin grafting and tissue replacement for treating foot ulcers in people with diabetes (2016) · Cochrane Headline outcomes only | RR 0.43 [0.23, 0.81] | 2 studies · 522 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Skin grafting and tissue replacement for treating foot ulcers in people with diabetes 2016 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.