Question · asked by 1 review

Glass ionomer-based sealant vs No comparator: Association between loss of complete retention risk and caries occurrence risk

Population
Patients with fissure-sealed permanent molar teeth
Intervention
Glass ionomer-based sealant
Comparison
No comparator
Outcome
Association between loss of complete retention risk and caries occurrence risk

Loss of complete retention was not directly associated with caries occurrence for glass-ionomer cement-based sealants in the main analysis (regression slope 0.81, 95% CI -0.07 to 1.68; ungraded).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Glass-ionomer cement-based fissure sealants vs No comparator (within-material surrogate-validity regression)
Association between loss of complete retention risk and caries occurrence risk · Patients with fissure-sealed permanent molar teeth · At least 24 months, Main analysis
Loss of complete retention was not directly associated with caries occurrence for glass-ionomer cement-based sealants in the main analysis (regression slope 0.81, 95% CI -0.07 to 1.68; ungraded).
Validity of sealant retention as surrogate for caries prevention--a systematic review. (2013) All outcomes
Regression slope (ln caries risk on ln retention-loss risk) 0.81 [-0.07, 1.68]22 studies · 3768 participantsGRADE not reported
Glass-ionomer cement-based fissure sealants vs No comparator (within-material surrogate-validity regression)
Association between loss of complete retention risk and caries occurrence risk · Patients with fissure-sealed permanent molar teeth · Longest follow-up per trial, Sensitivity analysis
In the sensitivity analysis, loss of complete retention was directly associated with caries occurrence for glass-ionomer cement-based sealants (regression slope 1.44, 95% CI 0.71 to 2.18; ungraded).
Validity of sealant retention as surrogate for caries prevention--a systematic review. (2013) All outcomes
Regression slope (ln caries risk on ln retention-loss risk) 1.44 [0.71, 2.18]14 studies · 2307 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Validity of sealant retention as surrogate for caries prevention--a systematic review.
2013 All outcomes
21 October 2012Not listedNot applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.