Question · asked by 1 review

COE with vital rinsing (toluidine blue/tolonium chloride) vs Conventional oral examination (COE) alone: Sensitivity (COE alone arm)

Population
Oral cavity cancer or potentially malignant disorder symptom-free individuals with tobacco habits
Intervention
COE with vital rinsing (toluidine blue/tolonium chloride)
Comparison
Conventional oral examination (COE) alone
Outcome
Sensitivity (COE alone arm)

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 1 · 50%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 0 · 0%
FindingEffectStudiesGRADE certainty
COE with vital rinsing (toluidine blue/tolonium chloride) vs Conventional oral examination (COE) alone
Sensitivity (COE alone arm) · OSCC or OPMD symptom-free individuals with tobacco habits
Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in… (2021) · Cochrane All outcomes
Sensitivity 0.50 [0.12, 0.88]1 study · 3895 participantsModerate
COE with vital rinsing (toluidine blue/tolonium chloride) vs Conventional oral examination (COE) alone
Sensitivity (COE alone arm) · Oral cavity cancer or potentially malignant disorder symptom-free individuals with tobacco habits
Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in… (2013) · Cochrane All outcomesearlier version CD010173.PUB2, superseded
Sensitivity 0.50 [0.12, 0.88]1 study · 3895 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults
2021 · Cochrane All outcomes
2020-10Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.