Question · asked by 1 review

Single‐dose, preoperative MMC‐EMDA vs TURBT alone: Serious adverse events

It is very uncertain whether single‐dose, preoperative MMC‐EMDA changes serious adverse events compared with TURBT alone (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Single‐dose, preoperative MMC‐EMDA vs TURBT alone
Serious adverse events
It is very uncertain whether single‐dose, preoperative MMC‐EMDA changes serious adverse events compared with TURBT alone (very low certainty).
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane Headline outcomes only
RR 1.74 [0.52, 5.77]1 study · 233 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.