Question · asked by 1 review

Beta‐2 agonists vs placebo: Cough

Beta‐2 agonists showed no clear difference in children: cough after seven days daily phone call compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Beta‐2 agonists vs placebo
Children: cough score after one day cough score · people with acute cough or a clinical diagnosis of acute bronchitis
Beta2‐agonists for acute cough or a clinical diagnosis of acute bronchitis (2015) · Cochrane Headline outcomes only
no estimate extracted2 studies · 96 participantsModerate
Beta‐2 agonists vs placebo
Children: cough score after three days cough score · people with acute cough or a clinical diagnosis of acute bronchitis
Beta2‐agonists for acute cough or a clinical diagnosis of acute bronchitis (2015) · Cochrane Headline outcomes only
no estimate extracted2 studies · 95 participantsModerate
Beta‐2 agonists vs placebo
Children: cough after seven days daily phone call · people with acute cough or a clinical diagnosis of acute bronchitis
Beta‐2 agonists showed no clear difference in children: cough after seven days daily phone call compared with placebo (moderate certainty).
Beta2‐agonists for acute cough or a clinical diagnosis of acute bronchitis (2015) · Cochrane Headline outcomes only
RR 0.89 [0.47, 1.68]1 study · 59 participantsModerate
Beta‐2 agonists vs placebo
Adults: cough after seven days diary · people with acute cough or a clinical diagnosis of acute bronchitis
Beta‐2 agonists showed no clear difference in adults: cough after seven days diary compared with placebo (low certainty).
Beta2‐agonists for acute cough or a clinical diagnosis of acute bronchitis (2015) · Cochrane Headline outcomes only
RR 0.86 [0.63, 1.18]3 studies · 220 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Beta2‐agonists for acute cough or a clinical diagnosis of acute bronchitis
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.