Cochrane · systematic review · CD001726
Beta2‐agonists for acute cough or a clinical diagnosis of acute bronchitis
Becker, LA, Hom, J, Villasis‐Keever, M, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 5 · 71.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Beta‐2 agonists versus placebo for acute bronchitis
Population: people with acute cough or a clinical diagnosis of acute bronchitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Children: cough score after one day cough score Beta‐2 agonists vs placebo | no estimate extracted | 2 studies · 96 participants | Moderate Downgraded: risk of bias, inconsistency |
Children: cough score after three days cough score Beta‐2 agonists vs placebo | no estimate extracted | 2 studies · 95 participants | Moderate Downgraded: risk of bias, inconsistency |
Children: cough after seven days daily phone call Beta‐2 agonists vs placebo | RR 0.89 [0.47, 1.68] | 1 study · 59 participants | Moderate Downgraded: risk of bias |
Children: shaking or tremor recorded/reported by parents Beta‐2 agonists vs placebo | RR 6.76 [0.86, 53.18] | 2 studies · 108 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Adults: cough after seven days diary Beta‐2 agonists vs placebo | RR 0.86 [0.63, 1.18] | 3 studies · 220 participants | Low Downgraded: imprecision, inconsistency |
Adults: night cough after seven days diary Beta‐2 agonists vs placebo | RR 0.84 [0.54, 1.33] | 3 studies · 210 participants | Moderate Downgraded: imprecision, inconsistency |
Adults: shaking, tremor or nervousness diary Beta‐2 agonists vs placebo | RR 7.94 [1.17, 53.94] | 3 studies · 211 participants | Low Downgraded: inconsistency |