Question · asked by 1 review

Summary of findings table ‐ Recombinant activated factor VII vs placebo: Thromboembolic events

Recombinant human factor VII activated showed no clear difference in thromboembolic events by patients compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Recombinant human factor VII activated vs placebo
Thromboembolic events by patients · patients with upper gastrointestinal bleeding and liver diseases.
Recombinant human factor VII activated showed no clear difference in thromboembolic events by patients compared with placebo (moderate certainty).
Human recombinant activated factor VII for upper gastrointestinal bleeding in patients with liver diseases (2012) · Cochrane Headline outcomes only
RR 0.8 [0.4, 1.6]2 studies · 507 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Human recombinant activated factor VII for upper gastrointestinal bleeding in patients with liver diseases
2012 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.