Warfarin vs placebo or no treatment: Major bleeding
Warfarin may leads to higher major bleeding eventsc compared with placebo or no treatment (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Warfarin vs placebo or no treatment Major bleeding eventsc · people with heart failure in sinus rhythm Warfarin may leads to higher major bleeding eventsc compared with placebo or no treatment (low certainty). Anticoagulation versus placebo for heart failure in sinus rhythm (2021) · Cochrane Headline outcomes only | OR 5.98 [1.71, 20.93] | 2 studies · 324 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Anticoagulation versus placebo for heart failure in sinus rhythm 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.