Summary of findings: ECM vs a different ECM: Abdominal pain frequency or change in frequency
- Population
- adults and children with cystic fibrosis
- Intervention
- Summary of findings: ECM
- Comparison
- a different ECM
- Outcome
- Abdominal pain frequency or change in frequency
Summary of findings: ECM (Creon®) showed no clear difference in frequency of bowel symptoms: proportion of days with abdominal pain compared with a different ECM (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: ECM (Creon®) vs a different ECM Frequency of bowel symptoms: proportion of days with abdominal pain · children and adults with cystic fibrosis Summary of findings: ECM (Creon®) showed no clear difference in frequency of bowel symptoms: proportion of days with abdominal pain compared with a different ECM (low certainty). Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane Headline outcomes only | MD 0 | 1 study · 83 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Summary of findings: ECM vs NECT plus cimetidine · adults with cystic fibrosis · 1 review
- Summary of findings: ECM vs ECT · adults and children with cystic fibrosis · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.