Budesonide 9 mg vs mesalamine: Clinical remission
Budesonide 9 mg probably leads to higher induction of clinical remission (CDAI < 150) ‐ 8 weeksThomsen 1998 compared with mesalamine (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Budesonide 9 mg vs mesalamine Induction of clinical remission (CDAI < 150) ‐ 8 weeksThomsen 1998 · Patients with active Crohn's disease Budesonide 9 mg probably leads to higher induction of clinical remission (CDAI < 150) ‐ 8 weeksThomsen 1998 compared with mesalamine (moderate certainty). Budesonide for induction of remission in Crohn's disease (2015) · Cochrane Headline outcomes only | RR 1.63 [1.23, 2.16] | 1 study · 182 participants | Moderate |
Budesonide 9 mg vs mesalamine Induction of clinical remission (CDAI < 150) ‐ 8 weeksTromm 2011 · Patients with active Crohn's disease Budesonide 9 mg showed no clear difference in induction of clinical remission (CDAI < 150) ‐ 8 weeksTromm 2011 compared with mesalamine (moderate certainty). Budesonide for induction of remission in Crohn's disease (2015) · Cochrane Headline outcomes only | RR 1.12 [0.95, 1.32] | 1 study · 307 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Budesonide for induction of remission in Crohn's disease 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.