Acyclovir vs placebo, vitamins, or no treatment: Minor adverse events not leading to withdrawal of treatment
- Population
- pityriasis rosea
- Intervention
- Acyclovir
- Comparison
- placebo, vitamins, or no treatment
- Outcome
- Minor adverse events not leading to withdrawal of treatment
Acyclovir showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo, vitamins, or no treatment (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Acyclovir vs placebo, vitamins, or no treatment Minor participant‐reported adverse events not requiring withdrawal of the treatment · pityriasis rosea Acyclovir showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo, vitamins, or no treatment (moderate certainty). Interventions for pityriasis rosea (2019) · Cochrane Headline outcomes only | RR 0.31 [0.01, 7.02] | 3 studies · 141 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for pityriasis rosea 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Acyclovir vs erythromycin · pityriasis rosea · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.