Synbiotic vs paraffin: Global assessment of treatment success
It is very uncertain whether synbiotics changes global improvement or treatment success, as defined by primary studies compared with paraffin (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Synbiotics vs paraffin Global improvement or treatment success, as defined by primary studies · children with chronic constipation without a physical explanation It is very uncertain whether synbiotics changes global improvement or treatment success, as defined by primary studies compared with paraffin (very low certainty). Probiotics for treatment of chronic constipation in children (2022) · Cochrane Headline outcomes only | RR 0.86 [0.65, 1.13] | 1 study · 60 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Probiotics for treatment of chronic constipation in children 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.