Question · asked by 1 review

Rivastigmine vs placebo: Acceptability

Rivastigmine probably leads to higher acceptability of treatment (as measured by withdrawals from trials… compared with placebo (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Rivastigmine vs placebo
Acceptability of treatment (as measured by withdrawals from trials before end of treatment at 26 weeks) · patients with Alzheimer's disease, mild to moderate
Rivastigmine probably leads to higher acceptability of treatment (as measured by withdrawals from trials… compared with placebo (moderate certainty).
Rivastigmine for Alzheimer's disease (2015) · Cochrane Headline outcomes onlyearlier version CD001191.PUB3, superseded
OR 2.01 [1.71, 2.37]7 studies · 3569 participantsModerate
Rivastigmine vs placebo
Acceptability of treatment (as measured by withdrawals from trials before end of treatment at 26 weeks) · patients with Alzheimer's disease, mild to moderate
Rivastigmine probably leads to higher acceptability of treatment (as measured by withdrawals from trials… compared with placebo (moderate certainty).
Rivastigmine for Alzheimer's disease (2015) · Cochrane Headline outcomes only
OR 2.01 [1.71, 2.37]7 studies · 3569 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Rivastigmine for Alzheimer's disease
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.