Question · asked by 1 review
Itraconazole vs Fluconazole: Empirical antifungal treatment
- Population
- Patients with cancer receiving chemotherapy and/or radiotherapy
- Intervention
- Itraconazole
- Comparison
- Fluconazole
- Outcome
- Empirical antifungal treatment
Itraconazole showed no clear difference in empirical antifungal treatment compared with fluconazole; GRADE not reported.
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Itraconazole vs Fluconazole Empirical antifungal treatment · Patients with cancer receiving chemotherapy or radiotherapy or both Itraconazole showed no clear difference in empirical antifungal treatment compared with fluconazole; GRADE not reported. Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2007) · Cochrane All outcomes | RR 0.5 [0.05, 5.43] | 1 study · 202 participants | GRADE not reported |
Itraconazole vs Fluconazole Empirical antifungal treatment · Patients with cancer receiving chemotherapy and/or radiotherapy Itraconazole showed no clear difference in empirical antifungal treatment compared with fluconazole; GRADE not reported. Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2004) · Cochrane All outcomesearlier version CD003807.PUB2, superseded | RR 0.5 [0.05, 5.43] | 1 study · 202 participants | GRADE not reported |
Itraconazole vs Fluconazole Empirical antifungal treatment · Patients with cancer receiving chemotherapy and/or radiotherapy Itraconazole showed no clear difference in empirical antifungal treatment compared with fluconazole; GRADE not reported. Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2002) · Cochrane All outcomesearlier version CD003807, superseded | RR 0.5 [0.05, 5.43] | 1 study · 202 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes | 2009-08 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.